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Think outside the box. Large, traditional companies often have rigid hiring processes, and no amount of out-of-the-box thinking will help you skirt around them. But if your target companies show any versatility, particularly if you want to work for a start-up, think of other ways to get their attention. Maybe it's through social media. Or a video resume. Or running a Google Adwords campaign. Rather than following the resume-cover letter-application route like most job seekers, figure out a way to get yourself ahead of the pack. Organizations want to hire smart, innovative people. Show you fall into both those categories, and you'll be well on your way to a new job.